The Mechanism of Development of the Antitumoral Immune Answer

 
 

The introduction of simulators of tumoral antigens
stimulates the production of antitumoral T-lymphocytes

Fig. 1
The antitumoral T-lymphocyte can bind  with only the
tumoral cell but does not bind with a normal cell

There is no close contact
Tcere is a close contact
Fig. 2
The search of tumor cells with a help of the antitumoral T-lumphocytes

The more the molecules of HLA-A on a tumoral cell, the better it is notable for the antitumoral T- lymphocyte
Fig. 3
The destruction of tumor cells by T-lymphocyte

After a close contact with tumor cell the T-lymphocyte starts to excrete perforins, which incorporate into the membrane of the tumor cell.
  

The perforins form a pore in the tumor cell. Through this pore water starts to enter into the tumor cell. The cell swells out, bursts off and dies, where as the T-lymphocyte searches for a new target cell for the next attack.
Fig. 4
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