After the vaccination, a specific anticancer immune response is triggered
in our body which maintains for next 6-12 months in an adequate level.
During the first and successive revaccinations even more vigorous
anticancer immune responses are triggered due to the T-memory cells
formed in the previous vaccination, which is held in an adequate level
for even longer period (5-7 years as shown in Fig.
1).
Revaccination is necessary to carry out in order
to regain and maintain the anticancer immune activities in an optimum
level.
The second vaccination is carried
out with a single dose of 600-1000 mg (3-5 vials) of RESAN. For the
revaccinations a packet of 4 vials (800 mg) of anticancer vaccine RESAN
is used. The content of each vial is dissolved in 1.0 millilitre 0.9
% solution of sodium chloride. The injections are carried out endermic,
in one shot, under a special scheme.
The second vaccination is carried
out after 6 months. The first revaccination is carried out
after 1.5. The successive revaccinations are carried
out in every 3-5 years.
In usual cases or in rational use of vaccine, after
the revaccination the anticancer immunity maintains in an adequate
level for next 5 years.
However, in case of the immunotherapy of advanced
cancers or immunotherapy of cancers with out surgical resections,
after the first revaccination the state of anticancer immunity
may become inefficient to stand against the remaining or new cancer
cells already after 1-2 years. In such cases, the second revaccination
is recommended after 1 years, and successive
revaccinations in every next 1-2 years in order to keep the antitumor
immune state in an adequate level.
