Аvailable Source: E.coli Official Symbol: IFNG Synonyms: Immune interferon, IFI, IFG, IFN gamma, IFN-γ AA Sequence: MQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQ SQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNV QRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ AA: 144 Mw: 16909.1 Da Purity: Greater than 98% by SDS-PAGE gel MAX OD280 0.1% solution: 0.678 MIN OD250 0.1% solution: 0.251 Biological Activity: The ED50 as determined by a cytopathic affect inhibition assay with cells challenged with VSV was 0.1 ng/ml, corresponding to a specific activity of 1 x 107 units/mg.   Stability: The lyophilized Recombinant Human Interferon-gamma is stable for at least 2 years from date of manufacture at -20oC. Reconstituted Interferon-gamma is stable for at least 3 months when stored in working aliquots with a carrier protein at -20oC. Avoid repeated freeze/thaw cycles. Summary: Interferon-gamma has important immunoregulatory functions. Interferon-gamma has antiviral and antiparasitic activities and also inhibits the proliferation of a number of normal and transformed cells. Interferon-gamma is an activator of macrophages and thus increases their antitumor activities. If the macrophages are infected by intracellular parasites, it activates macrophages which inturn destroy the parasites. Suppression of intracellular parasites under the influence of interferon-gamma takes place in other than macrophage cells as well. Price for 1 000 000 IU (lyophilized protein) – 35 $ (corresponding to a specific activity of 80 µg) The best Internet resources about Interferon-gamma: http://www.genecards.org/ http://www.ncbi.nlm.nih.gov/-1 http://www.ncbi.nlm.nih.gov/-2 http://www.ncbi.nlm.nih.gov/-3 http://www.hprd.org/ http://us.expasy.org/ http://www.uniprot.org/